Increasing prevalence of toxin A-negative, toxin B-positive isolates of Clostridium difficile in Korea: impact on laboratory diagnosis.

نویسندگان

  • Heejung Kim
  • Thomas V Riley
  • Myungsook Kim
  • Chang Ki Kim
  • Dongeun Yong
  • Kyungwon Lee
  • Yunsop Chong
  • Jong-Woo Park
چکیده

Of 462 Korean Clostridium difficile isolates, 77.5% were toxin B positive but 21.4% were toxin A negative (A(-) B(+)). The binary toxin gene was detected in nine isolates. A higher fluoroquinolone resistance of A(-) B(+) strains may contribute to the increase of these strains. Toxin A detection alone may underdiagnose C. difficile-associated disease.

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عنوان ژورنال:
  • Journal of clinical microbiology

دوره 46 3  شماره 

صفحات  -

تاریخ انتشار 2008